The Midland Certified Reagent Company, Incorporated
The Company for Quality DNA & RNA Oligos
 
 
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MODIFICATIONS
MIDLAND offers more than 100 DNA and RNA modifications. A modification is defined as any chemical entity covalently attached to synthetic DNA or RNA exclusive of the four major nucleotides present in each. Availability and price of many modifications are dependent upon supply of chemical materials and patent license agreements. Accordingly, certain modifications that have been described in the technical literature may not be available. However, over 100 modifications are routinely available. Please call or e-mail us for information concerning other modifications not listed below.

These are some of our most commonly requested modifications. To view the long list of modifications available from MIDLAND, click here. To contact us please click here.

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MODIFICATION PRICES
  At 3' - End or 5' - End50 nmole200 nmole1 mmole10 mmole
5' -Amino C3$25.00$30.00$60.00$250.00
3' - Amino C7$25.00$30.00$60.00$250.00
5' - Amino C6$25.00$30.00$60.00$250.00
  Internal Modifications50 nmole200 nmole1 mmole10 mmole
2-AminopurineN/A$318.00$365.00$1015.00
  3TERMMOD50 nmole200 nmole1 mmole10 mmole
Biotin-InternalN/A$210.00$260.00$950.00
  Internal Modifications50 nmole200 nmole1 mmole10 mmole
dIN/A$12.00$17.50$50.00
  At 3' - End or 5' - End50 nmole200 nmole1 mmole10 mmole
Digoxigenin (1)$175.00$180.00$230.00$750.00
  Internal Modifications50 nmole200 nmole1 mmole10 mmole
dUN/A$14.00$17.50$50.00
8-Oxo-dGN/A$200.00$250.00$450.00
8-Oxo-rGN/AN/A$740.00N/A
  At 3' - End or 5' - End50 nmole200 nmole1 mmole10 mmole
Phosphate$25.00$35.00$60.00$200.00
5' Thiol C6$60.00$75.00$100.00$300.00
Thiol Modifier C6 S-S$150.00$180.00$225.00$475.00

(1) Price includes the cost of the required amino group for attachment.

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