MIDLAND offers more than 100 DNA and RNA modifications. A modification is defined as any chemical entity covalently attached to synthetic DNA or RNA exclusive of the four major nucleotides present in each. Availability and price of many modifications are dependent upon supply of chemical materials and patent license agreements. Accordingly, certain modifications that have been described in the technical literature may not be available. However, over 100 modifications are routinely available. Please call or e-mail us for information concerning other modifications not listed below.
These are some of our most commonly requested modifications. To view the long list of modifications available from MIDLAND, click here. To contact us please click here.
IMPORTANT NEWS REGARDING ACETONITRILE:
CLICK THIS FOR INFORMATION REGARDING ACETONITRILE AND SURCHARGE.
'?TABLE?##
MODIFICATION
PRICES
Synthesis Scale
50
nmole
200
nmole
1
µmole
10
µmole
At
3' end or 5' end
Biotin
$45.00
$50.00
$90.00
$450.00
Phosphate
$25.00
$35.00
$60.00
$200.00
5'-
Amino C6
$25.00
$30.00
$60.00
$250.00
3'-
Amino C7
$25.00
$30.00
$60.00
$250.00
Digoxigenin*
$200.00
$210.00
$290.00
$950.00
Thiol
Modifier C6 S-S
$150.00
$180.00
$225.00
$475.00
5'-
Thiol
$60.00
$75.00
$100.00
$300.00
Internal
Modifications
dI
N/A
$14.00
$17.50
$50.00
dU
N/A
$14.00
$17.50
$50.00
Abasic
N/A
$120.00
$160.00
$420.00
2-Aminopurine
N/A
$160.00
$200.00
$450.00
8-Oxo-dG
N/A
$200.00
$250.00
$450.00
*Price includes the cost of the required amino group for attachment.